A two-dimensional sagittally symmetric human-body model was established to simulate an optimal trajectory for Home:Small Appliances:Handheld Mixers manual material handling tasks.Nonlinear control techniques and genetic algorithms were utilized in the optimizations to explore optimal lifting patterns.The simulation results were then compared with the experimental data.Since the kinetic measures such as joint TEXTURE BALM reactions and moments are vital parameters in injury determination, the importance of comparing kinetic measures rather than kinematical ones was emphasized.